3-NAntC: a novel Crotoxin Component B-derived peptide for the treatment of triple-negative breast cancera
Submited to Scientifc Report expected to April, 2023
An innovative company founded and managed by a highly-experienced team ...
... developed a novel technology based on a revolutionary new molecule with low toxicity and high efficacy called 3-NAntC...
... which turns into a breakthrough platform to treat aggressive solid tumors including, but not limited to, Triple Negative Breast Cancer
PHP Biotech was created to discover and develop an innovative approach to deal with solid cancers including, but probably not limited to, breast, lung, colorectal and pancreatic cancers, which are among the most diagnosed cancers worldwide. Current treatments have made progress against theses cancers, but not enough. With these unmet needs in mind, PHP Biotech research team has developed a pioneering compound (3-NAnTc) that is linked to a humanized single-domain antibody (sdAb) to enhance delivery and effectiveness in the fight against the most prevalent malignancies. Our technology allows multiple configurations of the sdAB, broadening the range of therapeutic possibilities and creating a platform of products to treat aggressive malignancies such as TNBC.
The molecule PHP Biotech developed has shown an ability to promote apoptosis while harnessing the development of metastatic disease allied with evidence of minimal toxicity. We envision 3-NAnTc being used as a monotherapy or as an add-on therapy against aggressive disease. Its favorable therapeutic ratio allows us to also consider its use in the maintenance setting so that patients can continue with their productive life while fighting their disease.
Medical Oncologist
Chicago. IL
Shareholder /
Board Member
Shareholder /
Board Member
Shareholder /
Board Member
Executive
Board Member
+20 Years of
experience
Executive Board Member
Executive Board Member
+20 Years of
experience
CEO
+30 Years of
experience
COO
+30 Years of
experience
CFO
Delivering innovation: 2020 oncology market outlook. McKinsey & Company / Data Bridge Market Research Market Analysys Study 2022/ https://dailynews.ascopubs.org/do/considering-high-unmet-need-triple-negative-breast-cancer, acessed in December 11th, 2022 / https://www.breastcancer.org/types/triple-negative, accessed on December 11th, 2022/ https://www.cancer.org/cancer/breast-cancer/about/types-of-breast-cancer/triple-negative.html, accessed on December 11th, 2022 / https://www.uptodate.com/contents/er-pr-negative-her2-negative-triple-negative-breast-cancer, accessed on December 11th, 2022
Submited to Scientifc Report expected to April, 2023